Dr. Somdutt Mujwar: Computational & Medicinal Chemistry Expert

Featured in Stanford University's Top 2% Scientists List for 2023 and 2024. Pioneering researcher combining computational methods with medicinal chemistry to develop innovative therapeutic solutions.

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Scientific Profile

Research Expertise & Specializations

Drug Design & Discovery

Specialized in computational approaches to drug development, including repurposing existing compounds for novel therapeutic applications. Expert in identifying potential drug candidates through advanced in silico modeling techniques.

Genomics & Target Identification

Applies genomics approaches to identify novel drug targets. Utilizes network pharmacology and systems biology to understand complex disease mechanisms and identify intervention points for therapeutic development.

Computational Modeling

Proficient in molecular docking, dynamic simulation, QSAR modeling, and pharmacophore development. Leverages R/Python programming for data mining and analysis of complex biological datasets to accelerate drug discovery.

Dr. Mujwar's interdisciplinary approach combines computational methods, medicinal chemistry, and biological validation to develop novel therapeutic agents. His work spans multiple disease areas with particular emphasis on cancer, infectious diseases, and neurological disorders.

Academic Background & Career Trajectory

1

Ph.D. in Bioinformatics (2013-2017)

Maulana Azad National Institute of Technology, Bhopal, India

Doctoral research focused on exploring riboswitches as pathogenic drug targets. Developed computational methods for designing molecules targeting bacterial riboswitches. Recipient of a prestigious Doctoral Fellowship funded by the Ministry of Human Resources Department, Government of India.

2

Faculty Positions (2017-Present)

Progressed from Assistant Professor at GLA University to Associate Professor at Chitkara University, establishing himself as a leading researcher in computational drug design. Developed computational drug design laboratory facilities and mentored numerous graduate students.

3

International Training (2024)

Completed a three-month Postdoctoral Internship at the University of Lodz, Poland, gaining hands-on training in advanced cell culture techniques for the evaluation of novel anticancer drugs, expanding his expertise beyond computational methods.

Throughout his career, Dr. Mujwar has maintained a consistent focus on integrating computational approaches with experimental validation, building a strong foundation for translational research in drug discovery and development.

Notable Research Contributions

Dr. Mujwar has made significant contributions to the field of computational and medicinal chemistry through his innovative research approaches. His work spans multiple therapeutic areas, with particular focus on:

Cancer Therapeutics

Conducted extensive research on anticancer mechanisms, including work on doxorubicin's multiple mechanisms of action and development of novel pyrazolo-tetrazolo-triazine sulfonamides with anticancer properties.

Neurodegenerative Diseases

Contributed to the development of indene-derived hydrazides targeting acetylcholinesterase for Alzheimer's disease treatment, combining computational design with biological evaluation.

Select Publications

With over 75 publications in peer-reviewed journals and a cumulative impact factor exceeding 230, Dr. Mujwar has established himself as a prolific researcher. His work appears in prestigious journals including BBA-Reviews on Cancer, International Journal of Molecular Sciences, and Computers in Biology and Medicine.

Cancer Research

Kciuk, M., Gielecińska, A., Mujwar, S., Kołat, D., et al. (2023). Doxorubicin—An Agent with Multiple Mechanisms of Anticancer Activity. Cells, 12(4), p.659. (IF: 7.666)

Gielecińska, A., Kciuk, M., Yahya, E.B., Ainane, T., Mujwar, S. and Kontek, R. (2023). Apoptosis, necroptosis, and pyroptosis as alternative cell death pathways induced by chemotherapeutic agents? Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, p.189024. (IF: 11.2)

Drug Design & Development

Kciuk, M., Mujwar, S., et al. (2022). Preparation of Novel Pyrazolo [4, 3-e] tetrazolo [1, 5-b][1, 2, 4] triazine Sulfonamides and Their Experimental and Computational Biological Studies. International Journal of Molecular Sciences, 23(11), 5892. (IF: 6.208)

Shinu, P., Sharma, M., Gupta, G.L., Mujwar, S., et al. (2022). Computational Design, Synthesis, and Pharmacological Evaluation of Naproxen-Guaiacol Chimera for Gastro-Sparing Anti-Inflammatory Response by Selective COX2 Inhibition. Molecules, 27(20), p.6905. (IF: 4.927)

Dr. Mujwar's publication record demonstrates his versatility as a researcher and his ability to apply computational methods to diverse therapeutic challenges. His work is characterized by a strong emphasis on translational potential and practical applications in drug discovery.

Technical Expertise & Methodological Approaches

Computational Methods

  • Molecular docking and dynamic simulation
  • Pharmacophore modeling and virtual screening
  • Quantitative Structure-Activity/Property Relationship (QSAR/QSPR)
  • Network pharmacology for systems-level analysis
  • Data mining and machine learning approaches

Programming & Software Skills

  • R and Python programming for data analysis
  • Specialized drug discovery software platforms
  • Statistical analysis and predictive modeling
  • Bioinformatics tools for sequence analysis
  • Structural biology visualization and analysis

Dr. Mujwar's technical expertise encompasses both theoretical understanding and practical application of computational tools in drug discovery. His programming skills allow him to develop custom solutions for complex research problems, while his knowledge of medicinal chemistry principles ensures biological relevance of computational predictions.

International Collaborations & Editorial Responsibilities

Research Collaborations

Dr. Mujwar maintains active research collaborations with scientists across multiple countries, including Poland, Morocco, and the United States. These international partnerships have resulted in numerous high-impact publications and expanded the scope of his research.

Editorial Board Memberships

Serves on the editorial boards of respected scientific journals including Acta Biochimica Polonica and Discover Molecules. In these roles, he contributes to maintaining scientific rigor and identifying cutting-edge research for publication.

Peer Review Activities

Regularly reviews manuscripts for numerous international journals in the fields of computational chemistry, medicinal chemistry, and drug discovery, helping to ensure the quality and integrity of published research.

Dr. Mujwar's international engagement reflects his standing in the global scientific community. Through these collaborations and editorial responsibilities, he contributes to the advancement of scientific knowledge and facilitates the exchange of ideas across national boundaries.

Research Methodology: From Computation to Validation

Dr. Mujwar employs a comprehensive, multi-stage approach to drug discovery that integrates computational prediction with experimental validation:

Target Identification

Using genomics and network pharmacology approaches to identify and validate potential drug targets associated with specific diseases.

In Silico Screening

Applying molecular docking, virtual screening, and pharmacophore modeling to identify promising compounds from large chemical libraries.

Optimization

Refining lead compounds through iterative computational modeling and structure-activity relationship studies to improve potency and selectivity.

Experimental Validation

Confirming computational predictions through laboratory testing, including cell culture experiments and biochemical assays to assess biological activity.

This integrated approach allows for more efficient drug discovery by focusing experimental resources on the most promising candidates identified through computational methods, accelerating the path from concept to potential therapeutic agent.

Awards & Recognition

2%

Stanford Top Scientists

Named among Stanford University's Top 2% Scientists globally for consecutive 3 years (2023 ,2024 and 2025), recognizing his significant impact on the field of computational and medicinal chemistry.

105+

Publications

Author of more than 75 peer-reviewed scientific publications in prestigious international journals, with a cumulative impact factor exceeding 230 and an h-index of 23.

31

H-Index

Achieved an impressive h-index of 23, reflecting both the productivity and citation impact of his research contributions to the scientific community.

Additional Honors

  • Young Scientist Award at the 3rd International Conference of IFIP in Bioinformatics
  • Doctoral Fellowship from the Ministry of Human Resources Department, Government of India
  • Invitations to serve as a keynote speaker at multiple international scientific conferences

These recognitions highlight Dr. Mujwar's standing as a leading researcher in computational and medicinal chemistry, with significant contributions to advancing the field through innovative methodologies and impactful research outcomes.

Contact & Collaboration Opportunities

Research Interests for Collaboration

  • Computational drug repurposing for emerging diseases
  • Novel anticancer drug development
  • AI/ML applications in drug discovery
  • Structural biology and molecular dynamics
  • Translational research in medicinal chemistry

Dr. Mujwar welcomes inquiries from potential collaborators, students, and industry partners interested in computational and medicinal chemistry research.

Contact Information

Location: Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India

Phone: +91 9827813303

Professional Profiles

Connect with Dr. Mujwar on LinkedIn, ResearchGate, Google Scholar, and ORCID for the latest updates on his research and publications.